What is the maximum thickness of a frozen section typically produced?

The maximum thickness of a frozen section typically produced is 10 micrometers. This thickness is optimal for providing sufficient detail for diagnostic purposes while allowing adequate penetration of the cutting tool and preservation of cellular morphology. In instances where thicker sections are cut, there could be challenges related to the clarity of the cellular detail, which is crucial for accurate diagnosis in a rapid intraoperative setting.

Frozen sections are often utilized during surgical procedures to provide immediate feedback about the nature of the tissue being examined. The thin sections help pathologists quickly assess whether further excision of tissue is needed. Thinner sections (like those around 5 micrometers) can provide excellent details, but when assessing larger structures or needing more cellular context, the 10 micrometer thickness balances quality and practicality effectively, ensuring overall accuracy in evaluation.